Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1xp6AIUEstrogen receptor

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1xp6AIUEstrogen receptor/1.000
1sj0E4DEstrogen receptor/0.608
1yinCM3Estrogen receptor/0.581
2pogWSTEstrogen receptor/0.507
1uomPTIEstrogen receptor/0.500
2jf9OHTEstrogen receptor/0.483
1xqcAEJEstrogen receptor/0.477
1errRALEstrogen receptor/0.470
1xpcAITEstrogen receptor/0.459
2gpvOHTEstrogen-related receptor gamma/0.442