Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453