sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1txi | TX5 | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1txi | TX5 | Vitamin D3 receptor | / | 1.000 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.830 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.753 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.742 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.714 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.701 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.688 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.685 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.678 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.678 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.676 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.672 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.670 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.666 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.666 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.664 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.662 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.662 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.658 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.658 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.657 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.657 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.656 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.656 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.653 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.652 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.651 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.651 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.651 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.650 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.650 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.649 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.648 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.648 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.646 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.646 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.643 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.642 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.637 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.637 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.636 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.636 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.636 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.635 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.634 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.634 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.634 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.633 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.633 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.631 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.630 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.630 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.629 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.627 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.627 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.625 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.623 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.622 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.620 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.616 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.616 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.613 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.613 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.611 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.609 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.608 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.606 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.604 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.598 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.598 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.462 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.450 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.450 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.449 | |
| 1osv | CHC | Bile acid receptor | / | 0.448 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.445 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.444 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.444 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.444 |