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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1rqjIPEFarnesyl diphosphate synthase2.5.1.10

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1rqjIPEFarnesyl diphosphate synthase2.5.1.101.000
1rqjRISFarnesyl diphosphate synthase2.5.1.100.905
3krfIPEGeranyl diphosphate synthase large subunit/0.553
4lfgIPEPutative geranyltranstransferase/0.534
3krfDSTGeranyl diphosphate synthase large subunit/0.526
4kqsIPEFarnesyl pyrophosphate synthase2.5.1.100.500
1zw5ZOLFarnesyl pyrophosphate synthase2.5.1.100.490
4kqsRISFarnesyl pyrophosphate synthase2.5.1.100.487
3oabDSTGeranyl diphosphate synthase large subunit/0.470
3ez3IPEFarnesyl pyrophosphate synthase, putative/0.463
4nkeRISFarnesyl pyrophosphate synthase2.5.1.100.463
4nkeIPEFarnesyl pyrophosphate synthase2.5.1.100.461
3ldwIPEFarnesyl pyrophosphate synthase, putative/0.456
2opmNI9Farnesyl pyrophosphate synthase2.5.1.100.452
4dwb0M7Farnesyl pyrophosphate synthase/0.450
4q23RISFarnesyl pyrophosphate synthase2.5.1.100.450
3ez3ZOLFarnesyl pyrophosphate synthase, putative/0.448
3rywK9HFarnesyl pyrophosphate synthase, putative/0.448
3dyh721Farnesyl pyrophosphate synthase/0.447
3egt722Farnesyl pyrophosphate synthase/0.444