sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1qtq	QSI	Glutamine--tRNA ligase	6.1.1.18

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1qtq	QSI	Glutamine--tRNA ligase	6.1.1.18	1.000
2re8	GSU	Glutamine--tRNA ligase	6.1.1.18	0.760
1qru	ATP	Glutamine--tRNA ligase	6.1.1.18	0.737
1gtr	ATP	Glutamine--tRNA ligase	6.1.1.18	0.687
2rd2	QSI	Glutamine--tRNA ligase	6.1.1.18	0.682
1euy	QSI	Glutamine--tRNA ligase	6.1.1.18	0.677
1qrs	ATP	Glutamine--tRNA ligase	6.1.1.18	0.675
1qrt	ATP	Glutamine--tRNA ligase	6.1.1.18	0.660
4jxx	ATP	Glutamine--tRNA ligase	6.1.1.18	0.647
4jyz	ATP	Glutamine--tRNA ligase	6.1.1.18	0.625
4jxz	ATP	Glutamine--tRNA ligase	6.1.1.18	0.601