sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1qf2	TI3	Thermolysin	3.4.24.27

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1qf2	TI3	Thermolysin	3.4.24.27	1.000
6tmn	0PI	Thermolysin	3.4.24.27	0.639
2tmn	0FA	Thermolysin	3.4.24.27	0.631
3t87	UBZ	Thermolysin	3.4.24.27	0.627
4tln	LNO	Thermolysin	3.4.24.27	0.617
4h57	0PJ	Thermolysin	3.4.24.27	0.613
3t8c	UBW	Thermolysin	3.4.24.27	0.612
3t74	UBY	Thermolysin	3.4.24.27	0.610
4tmn	0PK	Thermolysin	3.4.24.27	0.604
3fgd	BYA	Thermolysin	3.4.24.27	0.595
4d9w	X32	Thermolysin	3.4.24.27	0.592
3for	ZNP	Thermolysin	3.4.24.27	0.583
3t8d	UBV	Thermolysin	3.4.24.27	0.549
3t8h	UBS	Thermolysin	3.4.24.27	0.549
3f28	S7B	Thermolysin	3.4.24.27	0.470
3hyo	ADP	Pyridoxal kinase	/	0.441