sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1onf	FAD	Glutathione reductase	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1onf	FAD	Glutathione reductase	1.8.1.7	1.000
2r9z	FAD	Glutathione amide reductase	/	0.490
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.489
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.471
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.469
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.467
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.464
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.462
2gh5	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.459
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.456
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.450
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.450
2eq9	FAD	Dihydrolipoyl dehydrogenase	/	0.443
1zx9	FAD	Mercuric reductase	1.16.1.1	0.440