sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1n4q	LYS_CYS_VAL_ILE_LEU	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1n4q	LYS_CYS_VAL_ILE_LEU	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59	1.000
1s64	778	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59	0.531
1n4s	CYS_VAL_ILE_LEU_GER	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59	0.528
4gtr	7TR	Protein farnesyltransferase subunit beta	2.5.1.58	0.448
2h6i	CYS_VAL_LEU_SER_GER	Protein farnesyltransferase subunit beta	2.5.1.58	0.444
1ld8	U49	Protein farnesyltransferase subunit beta	2.5.1.58	0.440