sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1n4p	CYS_VAL_ILE_LEU_GER	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1n4p	CYS_VAL_ILE_LEU_GER	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59	1.000
1s64	778	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59	0.591
1n4s	CYS_VAL_ILE_LEU_GER	Geranylgeranyl transferase type-1 subunit beta	2.5.1.59	0.581
2h6i	CYS_VAL_LEU_SER_GER	Protein farnesyltransferase subunit beta	2.5.1.58	0.525
4gtv	7TR	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.469
4q71	FAD	Bifunctional protein PutA	/	0.459
3q7f	ED2	Uncharacterized protein	/	0.458
3sfy	3FY	Uncharacterized protein	/	0.458
2f0y	3MN	Protein farnesyltransferase subunit beta	2.5.1.58	0.453
3b70	NAP	Enoyl reductase LovC	1	0.450
3hxb	BD5	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.450
1o1t	2NH	Protein farnesyltransferase subunit beta	2.5.1.58	0.447
3af3	GCP	Pantothenate kinase	2.7.1.33	0.444
3e34	ED1	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	/	0.440
3e34	ED1	Protein farnesyltransferase subunit beta	2.5.1.58	0.440