sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1lke	DOG	Bilin-binding protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1lke	DOG	Bilin-binding protein	/	1.000
1lnm	DTX	Bilin-binding protein	/	0.593
3h2s	NDP	Putative NADH-flavin reductase	/	0.470
3tfu	PL8	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	2.6.1.62	0.453
4eyw	L0R	Carnitine O-palmitoyltransferase 2, mitochondrial	2.3.1.21	0.451
1c3x	8IG	Purine nucleoside phosphorylase	2.4.2.1	0.450
1zq5	E04	Aldo-keto reductase family 1 member C3	/	0.448
4a31	2CB	Glycylpeptide N-tetradecanoyltransferase	/	0.448
2wzy	SQX	Soluble acetylcholine receptor	/	0.446
4uug	PXG	Branched-chain amino acid aminotransferase, putative	/	0.446
3fhx	PLP	Pyridoxal kinase	2.7.1.35	0.445
2iej	S48	Protein farnesyltransferase subunit beta	2.5.1.58	0.443
3mjr	AC2	Deoxycytidine kinase	2.7.1.74	0.443
1szg	FNS	Cytochrome b2, mitochondrial	1.1.2.3	0.442
1ry0	PG2	Aldo-keto reductase family 1 member C3	/	0.441
3eks	CY9	Actin-5C	/	0.441