sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1kie | AD3 | IAG-nucleoside hydrolase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1kie | AD3 | IAG-nucleoside hydrolase | / | 1.000 | |
| 3b9g | IMH | IAG-nucleoside hydrolase | / | 0.479 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.459 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3htj | ET | EbrA repressor | / | 0.452 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.445 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.443 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.440 |