sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1kbj	FMN	Cytochrome b2, mitochondrial	1.1.2.3

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1kbj	FMN	Cytochrome b2, mitochondrial	1.1.2.3	1.000
1szg	FNS	Cytochrome b2, mitochondrial	1.1.2.3	0.570
1kbi	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.513
2oz0	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.505
1qcw	FNS	Cytochrome b2, mitochondrial	1.1.2.3	0.504
1szf	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.498
3giy	FMN	(S)-mandelate dehydrogenase	1.1.99.31	0.488
1gox	FMN	Peroxisomal (S)-2-hydroxy-acid oxidase	1.1.3.15	0.485
2e77	FMN	Lactate oxidase	/	0.461
5ebu	FMN	Lactate oxidase	/	0.460
2nli	FMN	Lactate oxidase	/	0.453