Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1jjtBDSBeta-lactamase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1jjtBDSBeta-lactamase/1.000
1jjeBYSBeta-lactamase/0.563
4c1fX8ZMetallo-beta-lactamase type 2/0.513
1dd6MCIMetallo-beta-lactamase type 2/0.509
1a8t061Metallo-beta-lactamase type 2/0.457
4hl2ZZ7Metallo-beta-lactamase type 2/0.454
4exsX8ZMetallo-beta-lactamase type 2/0.446
4pnmNU1Tankyrase-22.4.2.300.445