Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ipeNDPTropinone reductase 21.1.1.236

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ipeNDPTropinone reductase 21.1.1.2361.000
1ae1NAPTropinone reductase 1/0.498
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.490
4j7uNAPSepiapterin reductase1.1.1.1530.484
4j7xNAPSepiapterin reductase1.1.1.1530.477
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.476
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.474
4hwkNAPSepiapterin reductase1.1.1.1530.473
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.472
1xg5NAPDehydrogenase/reductase SDR family member 11/0.470
1oaaNAPSepiapterin reductase1.1.1.1530.465
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.464
2dteNAIGlucose 1-dehydrogenase related protein/0.463
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.461
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.458
1snyNAPLD36273p/0.457
1rwbNADGlucose 1-dehydrogenase1.1.1.470.456
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
5idwNAPShort-chain dehydrogenase/reductase SDR/0.455
2bd0NAPSepiapterin reductase/0.454
1x7hNDPPutative ketoacyl reductase1.3.10.453
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.449
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.449
4qecNAPElxO/0.447
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.442
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.441
5jlaNADPutative short-chain dehydrogenase/reductase/0.440