sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1i5e | U5P | Uracil phosphoribosyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 1.000 | |
| 3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.496 | |
| 3gep | 24H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.493 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.471 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.464 | |
| 1upu | U5P | Uracil phosphoribosyltransferase | / | 0.462 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.450 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.448 | |
| 3ggc | H26 | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.447 | |
| 5cyo | GDP | Septin-9 | / | 0.446 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.443 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4yqf | GDP | Septin-9 | / | 0.440 |