Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1f4gTP4Thymidylate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1f4gTP4Thymidylate synthase/1.000
1f4fTP3Thymidylate synthase/0.856
1dduCB3Thymidylate synthase/0.487
1tduCB3Thymidylate synthase/0.484
1fwmCB3Thymidylate synthase/0.477
4gevCB3Thymidylate synthase/0.466
2ftoCB3Thymidylate synthase/0.465
4knzCB3Thymidylate synthase/0.460
4fogC2FThymidylate synthase ThyA/0.452
3bhlTHGThymidylate synthase/0.446
4ez8DHFThymidylate synthase2.1.1.450.444
3bgxMEFThymidylate synthase/0.442
1tduDURThymidylate synthase/0.440