Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1dyiFOLDihydrofolate reductase1.5.1.3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1dyiFOLDihydrofolate reductase1.5.1.31.000
1ddsMTXDihydrofolate reductase1.5.1.30.678
4dfrMTXDihydrofolate reductase1.5.1.30.652
1dhjMTXDihydrofolate reductase1.5.1.30.637
1dyhDZFDihydrofolate reductase1.5.1.30.621
1jolFFODihydrofolate reductase1.5.1.30.618
1dyjDDFDihydrofolate reductase1.5.1.30.613
2drcMTXDihydrofolate reductase1.5.1.30.583
1re7FOLDihydrofolate reductase1.5.1.30.582
1ddrMTXDihydrofolate reductase1.5.1.30.572
1draMTXDihydrofolate reductase1.5.1.30.565
1rb2FOLDihydrofolate reductase1.5.1.30.522
3och2MXDihydrofolate reductase1.5.1.30.519
1rd7FOLDihydrofolate reductase1.5.1.30.503
1ra8FOLDihydrofolate reductase1.5.1.30.490
5hi6MTXDihydrofolate reductase/0.481
1ra3MTXDihydrofolate reductase1.5.1.30.480
4x5jFOLDihydrofolate reductase1.5.1.30.476
1rb3MTXDihydrofolate reductase1.5.1.30.474
1dhiMTXDihydrofolate reductase1.5.1.30.468
4x5iFOLDihydrofolate reductase1.5.1.30.468
3drcMTXDihydrofolate reductase1.5.1.30.459
1tdrMTXDihydrofolate reductase1.5.1.30.456
1drbMTXDihydrofolate reductase1.5.1.30.445
4x5hFOLDihydrofolate reductase1.5.1.30.444