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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1amoFADNADPH--cytochrome P450 reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1amoFADNADPH--cytochrome P450 reductase/1.000
4yaoFADNADPH--cytochrome P450 reductase/0.581
1ja1FADNADPH--cytochrome P450 reductase/0.569
4y9uFADNADPH--cytochrome P450 reductase/0.567
1tllFADNitric oxide synthase, brain1.14.13.390.540
3qfcFADNADPH--cytochrome P450 reductase/0.525
3qe2FADNADPH--cytochrome P450 reductase/0.522
3qfsFADNADPH--cytochrome P450 reductase/0.515
1j9zFADNADPH--cytochrome P450 reductase/0.513
3vo2FADFerredoxin--NADP reductase/0.488
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.488
1w87FADFerredoxin--NADP reductase1.18.1.20.476
2bpoFADNADPH--cytochrome P450 reductase/0.475
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.474
3ojxFADNADPH--cytochrome P450 reductase/0.470
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.469
3w5uFADFerredoxin/0.464
4c43FADFerredoxin--NADP reductase1.18.1.20.464
1f20FADNitric oxide synthase, brain1.14.13.390.458
1gjrFADFerredoxin--NADP reductase1.18.1.20.456
3fpkFADFerredoxin-NADP reductase/0.455
1bjkFADFerredoxin--NADP reductase1.18.1.20.452
1qgyFADFerredoxin--NADP reductase1.18.1.20.451
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.450
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.446
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.445
4fk8FADFerredoxin--NADP reductase/0.444
1h85FADFerredoxin--NADP reductase1.18.1.20.442
1gaqFADFerredoxin/0.441
3qftFADNADPH--cytochrome P450 reductase/0.441
1sm4FADFerredoxin--NADP reductase/0.440