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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1akwFMNFlavodoxin

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1akwFMNFlavodoxin/1.000
1akrFMNFlavodoxin/0.616
1azlFMNFlavodoxin/0.582
1bu5RBFFlavodoxin/0.560
5xraFMNCannabinoid receptor 1/0.557
3f6rFMNFlavodoxin/0.540
5fx2FMNFlavodoxin/0.540
1fx1FMNFlavodoxin/0.536
1j9gFMNFlavodoxin/0.530
1c7fFMNFlavodoxin/0.529
1j8qFMNFlavodoxin/0.518
1akuFMNFlavodoxin/0.510
3ojxFMNNADPH--cytochrome P450 reductase/0.499
2fx2FMNFlavodoxin/0.493
4y7cFMNNADPH--cytochrome P450 reductase/0.493
1wsbFMNFlavodoxin/0.492
5tgzFMNCannabinoid receptor 1/0.485
1ykgFMNSulfite reductase [NADPH] flavoprotein alpha-component/0.483
1xyvFMNFlavodoxin/0.475
1xyyFMNFlavodoxin/0.472
4z0pNDPNAD-dependent dehydrogenase/0.461
2fcrFMNFlavodoxin/0.459
3q9bB3NAcetylpolyamine amidohydrolase/0.456
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
2v13C40Renin3.4.23.150.449
2zi63D1Deoxycytidine kinase2.7.1.740.449
3ensENSCoagulation factor X3.4.21.60.447
4fx2FMNFlavodoxin/0.447
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
1j9zFMNNADPH--cytochrome P450 reductase/0.444
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.443
3reoSAH(Iso)eugenol O-methyltransferase2.1.1.1460.443
4b4vL34Bifunctional protein FolD/0.442
5cfn2BAStimulator of interferon genes protein/0.442