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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1agnNADAlcohol dehydrogenase class 4 mu/sigma chain1.1.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1agnNADAlcohol dehydrogenase class 4 mu/sigma chain1.1.1.11.000
4nfhNAJAlcohol dehydrogenase E chain1.1.1.10.509
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.479
1ht0NADAlcohol dehydrogenase 1C1.1.1.10.473
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.471
1u3vNADAlcohol dehydrogenase 1B1.1.1.10.456
2jhfNADAlcohol dehydrogenase E chain1.1.1.10.451
1adcPADAlcohol dehydrogenase E chain1.1.1.10.450