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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5l6wAGSLIM domain kinase 12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5l6wAGSLIM domain kinase 12.7.11.11.000
3qyw6PBMitogen-activated protein kinase 12.7.11.240.476
2exlGDMEndoplasmin/0.464
3q5lKX2Heat shock protein 83-1/0.454
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3gstGPRGlutathione S-transferase Mu 12.5.1.180.449
3a7jADPSerine/threonine-protein kinase 242.7.11.10.443
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4fryNADPutative signal-transduction protein with CBS domains/0.441
4gu610NFocal adhesion kinase 12.7.10.20.441
3qrmNK7Gag-Pol polyprotein3.4.23.160.440
4bcoT6QCyclin-dependent kinase 22.7.11.220.440