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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5iqaGNPBifunctional AAC/APH2.3.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5iqaGNPBifunctional AAC/APH2.3.11.000
5iqgGDPBifunctional AAC/APH2.3.10.682
5bylGCPBifunctional AAC/APH2.3.10.662
5iqhGNPBifunctional AAC/APH2.3.10.649
5iqbGNPBifunctional AAC/APH2.3.10.639
5iqdGNPBifunctional AAC/APH2.3.10.637
5iqiGNPBifunctional AAC/APH2.3.10.602
5iqeGNPBifunctional AAC/APH2.3.10.596
4orkGDPBifunctional AAC/APH2.3.10.551
5iqfGDPBifunctional AAC/APH2.3.10.517
2puiADPMethylthioribose kinase2.7.1.1000.467
4ix5ANPUncharacterized protein/0.467
5bn4ANPV-type ATP synthase alpha chain/0.461
1h83FADPolyamine oxidase1.5.3.140.458
3wowANPCasein kinase II subunit alpha2.7.11.10.451
2hq9FADMll6688 protein/0.449
3kpfFADPolyamine oxidase1.5.3.140.447
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.445
2pupADPMethylthioribose kinase2.7.1.1000.443
4asuADPATP synthase subunit alpha, mitochondrial/0.443
3gkjHC3Niemann-Pick C1 protein/0.442