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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5icfSAH(S)-norcoclaurine 6-O-methyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5icfSAH(S)-norcoclaurine 6-O-methyltransferase/1.000
3reoSAH(Iso)eugenol O-methyltransferase2.1.1.1460.576
3p9kSAHCaffeic acid O-methyltransferase/0.573
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.502
5jr3SAHCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.472
4a6dSAMAcetylserotonin O-methyltransferase2.1.1.40.468
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.465
3gxoSAHMitomycin biosynthesis 6-O-methyltransferase/0.461
3gwzSAHMitomycin biosynthesis 6-O-methyltransferase/0.451
4x3qSAHSibL/0.449
3i53SAH2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.446