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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5g3sFDAFlavin-dependent L-tryptophan oxidase VioA

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
5g3sFDAFlavin-dependent L-tryptophan oxidase VioA/1.000
5g3tFDAFlavin-dependent L-tryptophan oxidase VioA/0.620
4i58FADCyclohexylamine Oxidase/0.457
1tdoFADL-amino-acid oxidase1.4.3.20.454
2b9xFADPutative aminooxidase/0.442