sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fsx | ADP | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5fsx | ADP | Uncharacterized protein | / | 1.000 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.518 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.518 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.499 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.490 | |
| 3sii | A1R | Uncharacterized protein | / | 0.487 | |
| 3ewr | APR | Replicase polyprotein 1a | 3.4.22 | 0.480 | |
| 3sig | AR6 | Uncharacterized protein | / | 0.469 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.463 | |
| 5fsy | AR6 | Uncharacterized protein | / | 0.463 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.457 | |
| 2fav | APR | Nonstructural polyprotein pp1a | / | 0.451 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.448 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.441 |