sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5ez4 | NAD | Betaine-aldehyde dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5ez4 | NAD | Betaine-aldehyde dehydrogenase | / | 1.000 | |
| 5dib | NAD | Betaine-aldehyde dehydrogenase | / | 0.578 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.560 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.555 | |
| 1o00 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.530 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.518 | |
| 1a4z | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.506 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.503 | |
| 3n82 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.485 | |
| 4i8p | NAD | Aminoaldehyde dehydrogenase 1 | / | 0.483 | |
| 4gnz | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.472 | |
| 2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.470 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.458 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.456 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.449 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 1eqb | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.444 | |
| 3rhr | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.444 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.443 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 1nec | FMN | Oxygen-insensitive NAD(P)H nitroreductase | 1 | 0.442 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.441 |