Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5dx1SFGHistone-arginine methyltransferase CARM1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5dx1SFGHistone-arginine methyltransferase CARM1/1.000
5dx8SFGHistone-arginine methyltransferase CARM1/0.613
3b3fSAHHistone-arginine methyltransferase CARM1/0.589
5dxjSFGHistone-arginine methyltransferase CARM1/0.585
2y1wSFGHistone-arginine methyltransferase CARM1/0.581
2y1xSAHHistone-arginine methyltransferase CARM1/0.552
5dwqSFGHistone-arginine methyltransferase CARM1/0.536
5dxaSFGHistone-arginine methyltransferase CARM1/0.535
1f3lSAHProtein arginine N-methyltransferase 3/0.531
2v74SAHHistone-arginine methyltransferase CARM1/0.516
4c03SFGProtein arginine N-methyltransferase 6/0.488
2bzgSAHThiopurine S-methyltransferase2.1.1.670.469
4rv9SAHD-mycarose 3-C-methyltransferase/0.465
3bgiSAHThiopurine S-methyltransferase2.1.1.670.459
4qppSAHProtein arginine N-methyltransferase 6/0.456
5dstSAHProtein arginine N-methyltransferase 82.1.10.451
4e2xSAHMethyltransferase/0.450
4c04SFGProtein arginine N-methyltransferase 6/0.446
4necSAHPutative SAM-dependent methyltransferase/0.445