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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5aqzSGVHeat shock 70 kDa protein 1A

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
5aqzSGVHeat shock 70 kDa protein 1A/1.000
3m3z3F5Heat shock cognate 71 kDa protein/0.540
3fzm3GOHeat shock cognate 71 kDa protein/0.517
1ngiANPHeat shock cognate 71 kDa protein/0.500
3fzfATPHeat shock cognate 71 kDa protein/0.499
1ngjANPHeat shock cognate 71 kDa protein/0.491
3hscADPHeat shock cognate 71 kDa protein/0.483
1nghATPHeat shock cognate 71 kDa protein/0.482
1atsADPHeat shock cognate 71 kDa protein/0.467
1atrADPHeat shock cognate 71 kDa protein/0.464
2qwqADPHeat shock cognate 71 kDa protein/0.461
3ldlATP78 kDa glucose-regulated protein/0.461
2qwrANPHeat shock cognate 71 kDa protein/0.457
2qwnADPHeat shock cognate 71 kDa protein/0.450