scPDB - Distribution of Binding site Similarity values of 4z4p entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4z4p	SAH	Histone-lysine N-methyltransferase 2D	2.1.1.43

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4z4p	SAH	Histone-lysine N-methyltransferase 2D	2.1.1.43	1.000
5f59	SAH	Histone-lysine N-methyltransferase 2C	2.1.1.43	0.491
1kbq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.478
1gg5	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.471
1h66	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.464
1kbo	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.464
1bws	NDP	GDP-L-fucose synthase	/	0.454
1dxq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.451
4qen	SAH	Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4	2.1.1.43	0.451
3gwf	NAP	Cyclohexanone monooxygenase	/	0.449
3n0b	FAD	Flavin-dependent thymidylate synthase	2.1.1.148	0.447
5a9s	NAP	Putative dehydrogenase	/	0.447
1xe6	5FP	Plasmepsin-2	3.4.23.39	0.445
2fzn	FAD	Bifunctional protein PutA	1.5.5.2	0.445
1d4a	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.443
3lqf	NAD	Galactitol dehydrogenase	/	0.442
4e5y	NDP	GDP-L-fucose synthase	1.1.1.271	0.441
3f03	FMN	Pentaerythritol tetranitrate reductase	/	0.440