scPDB - Distribution of Binding site Similarity values of 4yr9 entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4yr9	NAD	L-threonine 3-dehydrogenase, mitochondrial	1.1.1.103

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4yr9	NAD	L-threonine 3-dehydrogenase, mitochondrial	1.1.1.103	1.000
3a1n	NAD	NDP-sugar epimerase	/	0.552
3a4v	NAD	NDP-sugar epimerase	/	0.515
2yy7	NAD	L-threonine dehydrogenase	/	0.501
5lc1	NAD	L-threonine 3-dehydrogenase	/	0.494
4lis	NAD	UDP-glucose 4-epimerase (Eurofung)	/	0.450
1e6w	NAD	3-hydroxyacyl-CoA dehydrogenase type-2	1.1.1.35	0.441