sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4wud | ANP | DNA gyrase subunit B |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4wud | ANP | DNA gyrase subunit B | / | 1.000 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.797 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.594 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.578 | |
| 1ei1 | ANP | DNA gyrase subunit B | / | 0.540 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.494 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.470 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.467 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.460 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.455 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.447 | |
| 5a3b | APR | SIR2 family protein | / | 0.446 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 3zkb | ANP | DNA gyrase subunit B | / | 0.443 | |
| 4duh | RLI | DNA gyrase subunit B | / | 0.440 |