Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4ube | 2FA | Adenosine kinase | 2.7.1.20 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
4ube | 2FA | Adenosine kinase | 2.7.1.20 | 1.000 | |
2pkk | 2FA | Adenosine kinase | 2.7.1.20 | 0.935 | |
2pkm | ADN | Adenosine kinase | 2.7.1.20 | 0.656 | |
3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.467 | |
3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.467 | |
4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.460 | |
4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.460 | |
4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.459 | |
4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.458 | |
4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.453 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.450 | |
1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
2hld | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.450 | |
2hld | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
2c27 | MA8 | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.447 | |
2p5u | NAD | UDP-glucose 4-epimerase | / | 0.445 | |
3b1p | NOS | PfkB carbohydrate kinase family protein | / | 0.444 | |
1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
1z71 | L17 | Prothrombin | 3.4.21.5 | 0.443 | |
3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
2ejz | SAH | Diphthine synthase | / | 0.441 |