Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4s34ANPMitogen-activated protein kinase 12.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4s34ANPMitogen-activated protein kinase 12.7.11.241.000
4s32ANPMitogen-activated protein kinase 12.7.11.240.570
4s33ANPMitogen-activated protein kinase 12.7.11.240.559
4h3qANPMitogen-activated protein kinase 12.7.11.240.506
4fv6E57Mitogen-activated protein kinase 12.7.11.240.500
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.495
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.489
4nifANPMitogen-activated protein kinase 12.7.11.240.485
2ojj82AMitogen-activated protein kinase 12.7.11.240.483
4fmqANPMitogen-activated protein kinase 12.7.11.240.473
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.462
3qyzZ8BMitogen-activated protein kinase 12.7.11.240.454
2cciATPCyclin-dependent kinase 22.7.11.220.451
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.451
4ii5ADPCyclin-dependent kinase 22.7.11.220.450
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.448
3i60E86Mitogen-activated protein kinase 12.7.11.240.448
4qnyANPMitogen activated protein kinase, putative/0.448
2y9qANPMitogen-activated protein kinase 12.7.11.240.446
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.444
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.440