sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4pne | SAH | Methyltransferase-like protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4pne | SAH | Methyltransferase-like protein | / | 1.000 | |
| 3t7t | SAH | Uncharacterized protein | / | 0.463 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.461 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.457 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.456 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.454 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.454 | |
| 1hzz | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.453 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.451 | |
| 3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.447 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.446 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.445 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.443 | |
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase | / | 0.443 | |
| 4qnu | GEK | tRNA U34 carboxymethyltransferase | / | 0.443 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.441 | |
| 2nr4 | FMN | Conserved protein | / | 0.441 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 |