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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4mwzSAMPhosphoethanolamine N-methyltransferase, putative

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/1.000
4iv0SAMPhosphoethanolamine N-methyltransferase, putative/0.586
4iv8SAMPhosphoethanolamine N-methyltransferase,putative/0.524
3uj8SFGPhosphoethanolamine N-methyltransferase/0.491
3uj7SAMPhosphoethanolamine N-methyltransferase/0.487
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.483
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.480
5bp7SAHSAM-dependent methyltransferase/0.479
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.469
4kdrSAHUbiquinone biosynthesis O-methyltransferase/0.465
4r6xSAHPhosphoethanolamine N-methyltransferase/0.465
3ha5SFGHydroxymycolate synthase MmaA42.1.10.458
4irnFADAnaB/0.458
5je3SAHMethyl transferase/0.453
3sxjSAMPutative methyltransferase/0.452
3t7sSAMUncharacterized protein/0.451
5je4SAHMethyl transferase/0.449
1ve3SAMUncharacterized protein/0.446
3oadLPORenin3.4.23.150.445
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.445
4fgzSAHPhosphoethanolamine N-methyltransferase/0.444
4q71FADBifunctional protein PutA/0.444