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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4l7f1V5Mitogen-activated protein kinase 82.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4l7f1V5Mitogen-activated protein kinase 82.7.11.241.000
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.476
4qnyANPMitogen activated protein kinase, putative/0.465
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.460
1pmn984Mitogen-activated protein kinase 102.7.11.240.452
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.448
4btjATPTau-tubulin kinase 12.7.11.10.444
4aqc88ATyrosine-protein kinase JAK2/0.441
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.441