sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4l4v | 1VY | Major histocompatibility complex class I-related gene protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4l4v | 1VY | Major histocompatibility complex class I-related gene protein | / | 1.000 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.481 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.467 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.455 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.449 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.446 | |
| 4j7h | TRH | PCZA361.3 | / | 0.446 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.445 | |
| 4j7g | TRH | PCZA361.3 | / | 0.444 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 |