Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4kvgGTPRas-related protein Rap-1A

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4kvgGTPRas-related protein Rap-1A/1.000
1zc3GNPRas-related protein Ral-A/0.625
1zc4GNPRas-related protein Ral-A/0.599
1lfdGNPGTPase HRas/0.578
4nyiGNPGTPase HRas/0.571
4o25GTPGTP-binding protein Rheb/0.558
4nyjGNPGTPase HRas/0.552
3e5hGNPRas-related protein Rab-28/0.549
1t91GTPRas-related protein Rab-7a/0.545
1m7bGTPRho-related GTP-binding protein RhoE/0.542
1kmqGNPTransforming protein RhoA/0.540
3oivGNPGTPase HRas/0.539
3bbpGTPRas-related protein Rab-6A/0.538
1yzqGNPRas-related protein Rab-6A/0.537
3tklGTPRas-related protein Rab-1A/0.534
2c5lGTPGTPase HRas/0.532
2gilGTPRas-related protein Rab-6A/0.532
3oesGNPGTPase RhebL1/0.532
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.530
1zbdGTPRas-related protein Rab-3A/0.529
3a58GNPGTP-binding protein RHO1/0.528
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.525
4dxaGSPRas-related protein Rap-1b/0.524
1cxzGSPTransforming protein RhoA/0.523
1xtsGTPGTP-binding protein Rheb/0.521
3lbnGNPGTPase HRas/0.521
3rs5GNPGTPase HRas/0.521
2ffqGSPRas-related protein Rab-6B/0.519
1vg8GNPRas-related protein Rab-7a/0.518
1yhnGTPRas-related protein Rab-7a/0.518
2zetGTPRas-related protein Rab-27B/0.513
3v4fGNPGTPase HRas/0.513
5dhaGNPGTP-binding nuclear protein Ran/0.512
4ol0GTPGTP-binding nuclear protein Ran/0.510
1uadGNPRas-related protein Ral-A/0.509
1g17GNPRas-related protein SEC4/0.508
1s1cGNPTransforming protein RhoA/0.502
5hpyGDPTransforming protein RhoA/0.502
3oiuGNPGTPase HRas/0.499
3lawGNPRas-related protein Rab-7a/0.498
4rkfGNPRas-related protein Rab-3/0.498
3w3zGTPGTP-binding nuclear protein Ran/0.497
4k81GTPGTPase HRas/0.497
3i3sGNPGTPase HRas/0.494
3l8yGNPGTPase HRas/0.494
3eg5GNPCell division control protein 42 homolog/0.493
3tnfGNPRas-related protein Rab-8A/0.493
5b2zGNPGTPase HRas/0.491
4dltGNPGTPase HRas/0.490
3rabGNPRas-related protein Rab-3A/0.489
4cymGCPRas-related protein Rab-32/0.489
4lhwGNPRas-related protein Rab-8A/0.487
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.485
3ddcGNPGTPase HRas/0.485
3kudGDPGTPase HRas/0.485
4qxaGTPRas-related protein Rab-9A/0.485
2clsGTPRho-related GTP-binding protein Rho6/0.483
4xvrGNPGTPase HRas/0.483
3th5GNPRas-related C3 botulinum toxin substrate 1/0.481
3ea5GDPGTP-binding nuclear protein Ran/0.480
3kucGDPRas-related protein Rap-1A/0.479
1gwnGTPRho-related GTP-binding protein RhoE/0.478
1xtrGNPGTP-binding protein Rheb/0.478
1a2bGSPTransforming protein RhoA/0.477
2gcpGSPRho-related GTP-binding protein RhoC/0.477
4dsoGSPGTPase KRas/0.476
5jljGNPGTP-binding nuclear protein Ran/0.475
4js0GNPCell division control protein 42 homolog/0.473
3bc1GNPRas-related protein Rab-27A/0.471
3nbzGTPGTP-binding nuclear protein Ran/0.471
3kz1GSPTransforming protein RhoA/0.470
4dsuGDPGTPase KRas/0.470
2rgcGNPGTPase HRas/0.469
1k5dGNPGTP-binding nuclear protein Ran/0.468
4dsnGCPGTPase KRas/0.468
3rs7GNPGTPase HRas/0.467
3tgpGNPGTPase HRas/0.467
1ibrGNPGTP-binding nuclear protein Ran/0.460
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.458
3pitGNPRas-related protein M-Ras/0.458
4mitGTPRho-related protein racC/0.457
2cl6CAGGTPase HRas/0.456
1e96GTPRas-related C3 botulinum toxin substrate 1/0.455
3a6pGTPGTP-binding nuclear protein Ran/0.453
3tsoGNPRas-related protein Rab-25/0.453
4dlwGNPGTPase HRas/0.453
4g0nGNPGTPase HRas/0.453
4hdqGNPRas-related protein Rap-1b/0.453
1oixGDPRas-related protein Rab-11A/0.452
2rgeGNPGTPase HRas/0.451
3oiwGNPGTPase HRas/0.450
3x1zGNPRas-related protein Rap-1b/0.450
4hdoGNPRas-related protein Rap-1b/0.450
2a5yATPCell death protein 4/0.449
3lbiGNPGTPase HRas/0.449
3rs0GNPGTPase HRas/0.448
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.446
2rgbGNPGTPase HRas/0.445
4gzmGSPRas-related C3 botulinum toxin substrate 1/0.443
3rs4GNPGTPase HRas/0.442
2fe4GDPRas-related protein Rab-6B/0.441
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.440