scPDB - Distribution of Binding site Similarity values of 4keb entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4keb	FOL	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4keb	FOL	Dihydrofolate reductase	1.5.1.3	1.000
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.622
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.615
4kfj	FOL	Dihydrofolate reductase	1.5.1.3	0.610
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.607
4m6k	FOL	Dihydrofolate reductase	1.5.1.3	0.589
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.587
3ghw	GHW	Dihydrofolate reductase	1.5.1.3	0.583
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.580
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	0.574
1ohj	COP	Dihydrofolate reductase	1.5.1.3	0.569
1u70	MTX	Dihydrofolate reductase	1.5.1.3	0.557
3gi2	GHW	Dihydrofolate reductase	1.5.1.3	0.552
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.552
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.536
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.530
1ohk	COP	Dihydrofolate reductase	1.5.1.3	0.529
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.526
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.525
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.520
3d80	Q22	Dihydrofolate reductase	1.5.1.3	0.520
3gyf	51P	Dihydrofolate reductase	1.5.1.3	0.520
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.515
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.510
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.508
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.507
3k45	51P	Dihydrofolate reductase	1.5.1.3	0.502
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.501
1dls	MTX	Dihydrofolate reductase	1.5.1.3	0.498
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.496
3nu0	3TU	Dihydrofolate reductase	1.5.1.3	0.496
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.494
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.491
1kmv	LII	Dihydrofolate reductase	1.5.1.3	0.490
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.486
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.481
1pd8	CO4	Dihydrofolate reductase	1.5.1.3	0.477
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.477
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.476
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.473
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.470
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.469
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.464
4kd7	9DR	Dihydrofolate reductase	1.5.1.3	0.464
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.460
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.455
3k47	D09	Dihydrofolate reductase	1.5.1.3	0.447