sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase | / | 1.000 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.491 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.480 | |
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.469 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.468 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.466 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.463 | |
| 5d4u | SAM | Uncharacterized protein MJ0489 | / | 0.463 | |
| 5dp2 | NAP | CurF | / | 0.461 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.459 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.457 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.457 | |
| 5je3 | SAH | Methyl transferase | / | 0.456 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.453 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.453 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.448 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 3dh0 | SAM | Uncharacterized protein | / | 0.447 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.444 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 4ax8 | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.440 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.440 |