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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4jxrACOAcetyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4jxrACOAcetyltransferase/1.000
3dr8ACOL-methionine sulfoximine/L-methionine sulfone acetyltransferase/0.496
4jwpACOGCN5-related N-acetyltransferase/0.491
5dp2NAPCurF/0.467
4lx9ACON-alpha-acetyltransferase2.3.10.464
4kvmSER_ALA_SER_GLU_1XEN-terminal acetyltransferase A complex catalytic subunit ard12.3.1.880.462
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.459
2gv8NDPThiol-specific monooxygenase1.14.130.457
4kvxACON-terminal acetyltransferase A complex catalytic subunit ard12.3.1.880.457
4u9vACON-alpha-acetyltransferase 402.3.10.451
1gheACOAcetyltransferase2.3.10.450
4hmsFMNPhenazine biosynthesis protein PhzG1.40.444
1j4jACOAcetyltransferase2.3.10.440
1yqxNAPSinapyl alcohol dehydrogenase/0.440
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.440