sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4js0 | GNP | Cell division control protein 42 homolog |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4js0 | GNP | Cell division control protein 42 homolog | / | 1.000 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.607 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.573 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.573 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.572 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.555 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.550 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.542 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.536 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.532 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.528 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.528 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.527 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.526 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.523 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.522 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.521 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.517 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.514 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.513 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.512 | |
| 4nyj | GNP | GTPase HRas | / | 0.512 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.512 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.510 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.508 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.508 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.508 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.504 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.502 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.502 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.500 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.498 | |
| 3v4f | GNP | GTPase HRas | / | 0.497 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.496 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.495 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.495 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.493 | |
| 4mit | GTP | Rho-related protein racC | / | 0.493 | |
| 3lbn | GNP | GTPase HRas | / | 0.491 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.491 | |
| 4nyi | GNP | GTPase HRas | / | 0.491 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.490 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.490 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.488 | |
| 2c5l | GTP | GTPase HRas | / | 0.484 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.483 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.483 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.481 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.481 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.478 | |
| 4k81 | GTP | GTPase HRas | / | 0.477 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.477 | |
| 2rge | GNP | GTPase HRas | / | 0.475 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.475 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.474 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.474 | |
| 3ddc | GNP | GTPase HRas | / | 0.473 | |
| 3oiu | GNP | GTPase HRas | / | 0.469 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.469 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.468 | |
| 3oiv | GNP | GTPase HRas | / | 0.467 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 2rgc | GNP | GTPase HRas | / | 0.465 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.465 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.464 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.464 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.463 | |
| 4itr | GDP | Cell division control protein 42 homolog | / | 0.461 | |
| 5b2z | GNP | GTPase HRas | / | 0.461 | |
| 2rgb | GNP | GTPase HRas | / | 0.459 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.457 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.457 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.457 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.455 | |
| 4dlt | GNP | GTPase HRas | / | 0.453 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.452 | |
| 3i3s | GNP | GTPase HRas | / | 0.452 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.451 | |
| 3rs5 | GNP | GTPase HRas | / | 0.451 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.450 | |
| 4g0n | GNP | GTPase HRas | / | 0.450 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.449 | |
| 3l8y | GNP | GTPase HRas | / | 0.449 | |
| 3lbh | GNP | GTPase HRas | / | 0.448 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.447 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.447 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.446 | |
| 4oi2 | ADP | Protein clpf-1 | / | 0.444 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.443 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.443 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.442 | |
| 3rs7 | GNP | GTPase HRas | / | 0.440 |