sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4jd5 | TZD | Benzoylformate decarboxylase | 4.1.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4jd5 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 1.000 | |
| 4gm0 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.740 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.715 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.713 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.699 | |
| 4qel | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.668 | |
| 1bfd | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.594 | |
| 4mq5 | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.579 | |
| 5dgt | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.571 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.563 | |
| 4ju8 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.560 | |
| 2fwn | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.557 | |
| 4mzx | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.557 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.544 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.532 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.524 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.520 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.505 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.496 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.484 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.480 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.478 | |
| 4ju9 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.477 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.460 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.459 | |
| 4pt0 | NAD | Aldehyde dehydrogenase | / | 0.459 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.457 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.457 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.456 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.455 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.453 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.452 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.452 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 4fgr | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.451 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.451 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 1glf | ADP | Glycerol kinase | / | 0.449 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.449 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 2rc3 | NAD | CBS domain | / | 0.448 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.448 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.444 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.443 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.442 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.441 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 1zpt | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.440 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.440 |