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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4h2nFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4h2nFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/1.000
3almFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.607
3gmbFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.605
3aljFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.602
4jy2FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.575
4h2pFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.510
5eowFAD6-hydroxynicotinate 3-monooxygenase1.14.13.1140.509
3allFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.503
4bjzFADProbable salicylate monooxygenase/0.471
1i3mUD1UDP-glucose 4-epimerase/0.445
1j39UPGDNA beta-glucosyltransferase/0.445
2x0rNADMalate dehydrogenase/0.445