sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 1.000 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.466 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.462 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.458 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.454 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.453 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.449 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.447 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.441 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.440 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.440 |