Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fx9FADCoenzyme A disulfide reductase1.8.1.14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fx9FADCoenzyme A disulfide reductase1.8.1.141.000
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.474
3cgbFADCoenzyme A disulfide reductase/0.467
3ic9FADPutative dihydrolipoamide dehydrogenase/0.467
4eqsFADCoenzyme A disulfide reductase/0.466
4ocgFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.459
2cfyFADThioredoxin reductase 1, cytoplasmic1.8.1.90.458
3icsFADCoenzyme A disulfide reductase/0.457
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.456
4jq9FADDihydrolipoyl dehydrogenase/0.452
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.451
3cgcFADCoenzyme A disulfide reductase/0.445
1yqzFADCoenzyme A disulfide reductase/0.442
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.442
4h50FADBiphenyl dioxygenase ferredoxin reductase subunit/0.442