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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fvzH4BNitric oxide synthase, brain1.14.13.39

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4fvzH4BNitric oxide synthase, brain1.14.13.391.000
4luxH4BNitric oxide synthase, brain1.14.13.390.785
1k2tH4BNitric oxide synthase, brain1.14.13.390.780
1k2uH4BNitric oxide synthase, brain1.14.13.390.778
3nlnH4BNitric oxide synthase, brain1.14.13.390.755
2hx4H4BNitric oxide synthase, brain1.14.13.390.752
4jshH4BNitric oxide synthase, brain1.14.13.390.743
3pngH4BNitric oxide synthase, brain1.14.13.390.742
3ufqH4BNitric oxide synthase, brain1.14.13.390.735
4fvxH4BNitric oxide synthase, brain1.14.13.390.730
3fc5H4BNitric oxide synthase, brain1.14.13.390.723
4jsiH4BNitric oxide synthase, brain1.14.13.390.709
3rqmH4BNitric oxide synthase, brain1.14.13.390.704
3jx5H4BNitric oxide synthase, brain1.14.13.390.702
3nnzH4BNitric oxide synthase, brain1.14.13.390.701
2g6iHBINitric oxide synthase, brain1.14.13.390.700
5aglH4BNitric oxide synthase, brain1.14.13.390.691
1om5H4BNitric oxide synthase, brain1.14.13.390.686
3b3nH4BNitric oxide synthase, brain1.14.13.390.685
3jt9H4BNitric oxide synthase, brain1.14.13.390.684
3b3oH4BNitric oxide synthase, brain1.14.13.390.682
3jx3H4BNitric oxide synthase, brain1.14.13.390.677
3jx2H4BNitric oxide synthase, brain1.14.13.390.675
1mmvH4BNitric oxide synthase, brain1.14.13.390.670
3nlpH4BNitric oxide synthase, brain1.14.13.390.670
3jwvH4BNitric oxide synthase, brain1.14.13.390.663
3q9aH4BNitric oxide synthase, brain1.14.13.390.662
3ufuH4BNitric oxide synthase, brain1.14.13.390.659
4fvyH4BNitric oxide synthase, brain1.14.13.390.659
3jt8H4BNitric oxide synthase, brain1.14.13.390.657
3jt6H4BNitric oxide synthase, brain1.14.13.390.651
4cx3H4BNitric oxide synthase, brain1.14.13.390.651
3jt5H4BNitric oxide synthase, brain1.14.13.390.650
5agkH4BNitric oxide synthase, brain1.14.13.390.650
3n5vH4BNitric oxide synthase, brain1.14.13.390.648
3jtaH4BNitric oxide synthase, brain1.14.13.390.646
3jt3H4BNitric oxide synthase, brain1.14.13.390.644
3jt7H4BNitric oxide synthase, brain1.14.13.390.643
3ufvH4BNitric oxide synthase, brain1.14.13.390.641
4jsfH4BNitric oxide synthase, brain1.14.13.390.641
1zzrH4BNitric oxide synthase, brain1.14.13.390.640
4cx5H4BNitric oxide synthase, brain1.14.13.390.640
3n5yH4BNitric oxide synthase, brain1.14.13.390.637
3jt4H4BNitric oxide synthase, brain1.14.13.390.636
3pnfH4BNitric oxide synthase, brain1.14.13.390.635
3hsnH4BNitric oxide synthase, brain1.14.13.390.633
4k5dH4BNitric oxide synthase, brain1.14.13.390.630
1p6kH4BNitric oxide synthase, brain1.14.13.390.629
3tymH4BNitric oxide synthase, brain1.14.13.390.629
5agpH4BNitric oxide synthase, brain1.14.13.390.626
4k5eH4BNitric oxide synthase, brain1.14.13.390.624
1rs7H4BNitric oxide synthase, brain1.14.13.390.623
1zzqH4BNitric oxide synthase, brain1.14.13.390.622
3tylH4BNitric oxide synthase, brain1.14.13.390.622
4jsgH4BNitric oxide synthase, brain1.14.13.390.622
2g6j7APNitric oxide synthase, brain1.14.13.390.619
4k5gH4BNitric oxide synthase, brain1.14.13.390.619
3q99H4BNitric oxide synthase, brain1.14.13.390.617
1rs6H4BNitric oxide synthase, brain1.14.13.390.616
3jwtH4BNitric oxide synthase, brain1.14.13.390.616
3ufpH4BNitric oxide synthase, brain1.14.13.390.616
3ufrH4BNitric oxide synthase, brain1.14.13.390.616
3jwuH4BNitric oxide synthase, brain1.14.13.390.615
2hx3H4BNitric oxide synthase, brain1.14.13.390.614
3b3pH4BNitric oxide synthase, brain1.14.13.390.614
3rqkH4BNitric oxide synthase, brain1.14.13.390.612
1m00H4BNitric oxide synthase, brain1.14.13.390.611
3rqjH4BNitric oxide synthase, brain1.14.13.390.611
4euxH4BNitric oxide synthase, brain1.14.13.390.611
3ufwH4BNitric oxide synthase, brain1.14.13.390.609
3dqrH4BNitric oxide synthase, brain1.14.13.390.608
4cx4H4BNitric oxide synthase, brain1.14.13.390.608
3nloH4BNitric oxide synthase, brain1.14.13.390.606
3nnyH4BNitric oxide synthase, brain1.14.13.390.604
3nlwH4BNitric oxide synthase, brain1.14.13.390.603
3nlkH4BNitric oxide synthase, brain1.14.13.390.602
3svqH4BNitric oxide synthase, brain1.14.13.390.602
3n5zH4BNitric oxide synthase, brain1.14.13.390.600
3nosH4BNitric oxide synthase, endothelial1.14.13.390.600
3pneH4BNitric oxide synthase, brain1.14.13.390.600
3nlzH4BNitric oxide synthase, brain1.14.13.390.599
3ufoH4BNitric oxide synthase, brain1.14.13.390.596
1zvlH4BNitric oxide synthase, brain1.14.13.390.595
1zzuH4BNitric oxide synthase, brain1.14.13.390.595
3nlqH4BNitric oxide synthase, brain1.14.13.390.592
1k2sH4BNitric oxide synthase, brain1.14.13.390.591
3svpH4BNitric oxide synthase, brain1.14.13.390.590
4gqeH4BNitric oxide synthase, brain1.14.13.390.588
4fw0H4BNitric oxide synthase, brain1.14.13.390.582
3e7gH4BNitric oxide synthase, inducible1.14.13.390.580
3nlrH4BNitric oxide synthase, brain1.14.13.390.576
3nljH4BNitric oxide synthase, brain1.14.13.390.575
4k5fH4BNitric oxide synthase, brain1.14.13.390.575
3jx6H4BNitric oxide synthase, brain1.14.13.390.574
3rqlH4BNitric oxide synthase, brain1.14.13.390.569
3ufsH4BNitric oxide synthase, brain1.14.13.390.567
3uftH4BNitric oxide synthase, brain1.14.13.390.564
3b3mH4BNitric oxide synthase, brain1.14.13.390.561
3ej8H4BNitric oxide synthase, inducible1.14.13.390.560
3jx4H4BNitric oxide synthase, brain1.14.13.390.558
4d1oH4BNitric oxide synthase, endothelial1.14.13.390.557
2nodH4BNitric oxide synthase, inducible1.14.13.390.556
4imtH4BNitric oxide synthase, brain1.14.13.390.555
1p6jH4BNitric oxide synthase, brain1.14.13.390.550
3nlvH4BNitric oxide synthase, brain1.14.13.390.550
3nlyH4BNitric oxide synthase, brain1.14.13.390.546
1dwxH4BNitric oxide synthase, inducible1.14.13.390.545
3nodH4BNitric oxide synthase, inducible1.14.13.390.544
3e6tH4BNitric oxide synthase, inducible1.14.13.390.535
4imuH4BNitric oxide synthase, brain1.14.13.390.534
3dwjH4BNitric oxide synthase, inducible1.14.13.390.532
1r35H4BNitric oxide synthase, inducible1.14.13.390.531
3e6oH4BNitric oxide synthase, inducible1.14.13.390.526
3n61H4BNitric oxide synthase, brain1.14.13.390.525
4imwH4BNitric oxide synthase, brain1.14.13.390.525
4jseH4BNitric oxide synthase, brain1.14.13.390.511
3nw2H4BNitric oxide synthase, inducible1.14.13.390.510
1m8eH4BNitric oxide synthase, inducible1.14.13.390.501
1qomH4BNitric oxide synthase, inducible1.14.13.390.492
3n63XFNNitric oxide synthase, brain1.14.13.390.478
3e67H4BNitric oxide synthase, inducible1.14.13.390.471
1m9tH4BNitric oxide synthase, inducible1.14.13.390.466
1vafH4BNitric oxide synthase, inducible1.14.13.390.459
3n66XFNNitric oxide synthase, brain1.14.13.390.455