Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4f31KAIGlutamate receptor 3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4f31KAIGlutamate receptor 3/1.000
1fw0KAIGlutamate receptor 2/0.631
4f3gKAIGlutamate receptor 3/0.580
1lbbKAIGlutamate receptor 2/0.579
3c35KAIGlutamate receptor ionotropic, kainate 1/0.519
3c36KAIGlutamate receptor ionotropic, kainate 1/0.503
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.497
3c34KAIGlutamate receptor ionotropic, kainate 1/0.490
4bdrKAIGlutamate receptor ionotropic, kainate 2/0.478
2b82ADNClass B acid phosphatase3.1.3.20.474
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
1knpFADL-aspartate oxidase1.4.3.160.464
4h3j10WBeta-secretase 13.4.23.460.458
1gky5GPGuanylate kinase2.7.4.80.448
2yac937Serine/threonine-protein kinase PLK12.7.11.210.444
3ig6438Urokinase-type plasminogen activator3.4.21.730.444
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.444
4djy0KRBeta-secretase 13.4.23.460.444
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.443
4friDWABeta-secretase 13.4.23.460.443
3ojxFMNNADPH--cytochrome P450 reductase/0.442
1vyrFMNPentaerythritol tetranitrate reductase/0.440
2gv8NDPThiol-specific monooxygenase1.14.130.440
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.440
4b78KGGBeta-secretase 13.4.23.460.440