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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4exsX8ZMetallo-beta-lactamase type 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4exsX8ZMetallo-beta-lactamase type 2/1.000
4c1fX8ZMetallo-beta-lactamase type 2/0.510
4hl1ZZ7Metallo-beta-lactamase type 2/0.487
4hl2ZZ7Metallo-beta-lactamase type 2/0.485
1dd6MCIMetallo-beta-lactamase type 2/0.483
4h0dZZ7Metallo-beta-lactamase type 2/0.480
1u1f183Uridine phosphorylase2.4.2.30.472
3iogSDFMetallo-beta-lactamase type 2/0.460
1hlk113Metallo-beta-lactamase type 2/0.458
4c1hX8ZMetallo-beta-lactamase type 2/0.458
4rawZZ7Metallo-beta-lactamase type 2/0.456
2vcxD26Hematopoietic prostaglandin D synthase/0.447
4a83DXCMajor pollen allergen Bet v 1-A/0.444
1r8qAFBCytohesin-2/0.441
1r8qAFBADP-ribosylation factor 1/0.441