sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4eht | ADP | 2-hydroxyisocaproyl-CoA dehydratase activator |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4eht | ADP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 1.000 | |
| 4ehu | ANP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 0.625 | |
| 1hux | ADP | Activator of (R)-2-hydroxyglutaryl-CoA dehydratase | / | 0.469 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.456 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.455 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.453 | |
| 3daw | ATP | Actin, alpha skeletal muscle | / | 0.451 | |
| 1s22 | ATP | Actin, alpha skeletal muscle | / | 0.450 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.449 | |
| 4cbx | ATP | Actin-2 | / | 0.449 | |
| 3m9v | TYD | FAD-dependent oxidoreductase | / | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 4pkh | ADP | Actin, alpha skeletal muscle | / | 0.443 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.442 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.442 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.442 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.441 |